1. Signaling Pathways
  2. PROTAC
  3. Ligands for E3 Ligase
  4. Ligands for E3 Ligase Inhibitors

Ligands for E3 Ligase Inhibitors

von Hippel-Lindau (VHL)

MDM2

Cereblon

IAP

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Ligands for E3 Ligase Modulators
Product Name von Hippel-Lindau (VHL) MDM2 Cereblon IAP Purity
Lenalidomide    
Cereblon
  99.95%
Pomalidomide    
Cereblon
  99.96%
Eragidomide    
Cereblon
  99.86%
VH032
VHL
      99.64%
(S,R,S)-AHPC-Me hydrochloride
VHL
      99.59%
(S,R,S)-AHPC monohydrochloride
VHL
      99.83%
Cemsidomide    
Cereblon, Kd: 0.9 nM
  98.94%
Golcadomide    
Cereblon
 
(S,R,S)-AHPC
VHL
      99.13%
Lenalidomide hemihydrate    
Cereblon
  99.67%
VH032-cyclopropane-F
VHL
      99.92%
(S,R,S)-AHPC-Me
VHL
      99.48%
Lenalidomide-Br    
Cereblon
  99.86%
(S,S,S)-AHPC hydrochloride
VHL
      99.90%
Lenalidomide-OH    
Cereblon
  99.48%
(S)-Thalidomide    
Cereblon
  99.65%
cIAP1 ligand 1      
cIAP1
99.90%
VHL Ligand 8
VHL
     
VL285
VHL
      98.84%
Nutlin carboxylic acid  
MDM2
    98.63%
KB02-COOH    
Cereblon
  99.39%
Biotin-Thalidomide    
Cereblon
  99.65%
(S,R,S)-AHPC-Boc
VHL
     
CC-17369    
Cereblon
  98.13%
(S,R,S)-AHPC-Me dihydrochloride
VHL
      99.84%
VH 101, thiol
VHL
      98.66%
Cereblon inhibitor 1    
Cereblon
  99.19%
CRBN modulator-1    
Cereblon
  98.00%
2-Methoxyphenyl dihydrouracil    
Cereblon
 
Thalidomide-piperazine hydrochloride    
Cereblon
  98.27%
VH032 thiol
VHL
     
Pomalidomide-5-OH    
Cereblon
  99.46%
E3 ligase Ligand 23    
Cereblon
  99.71%
(R)-Thalidomide    
Cereblon
  99.80%
Lenalidomide hydrochloride    
Cereblon
 
(S,R,S)-AHPC TFA
VHL
     
E3 ligase Ligand 22    
Cereblon
 
Pomalidomide-5-O-CH3    
Cereblon
 
DA-PROTAC
VHL
     
(4R,5S)-Nutlin carboxylic acid  
MDM2
   
PROTAC CRBN ligand-2    
Cereblon
 
E3 ligase Ligand PG    
Cereblon, IC50: 2.191 μM
 
Thalidomide-d4    
Cereblon
  98.03%
Bestatin-amido-Me      
cIAP1
E3 ligase Ligand 21    
Cereblon
 
MV-1-NH-Me      
cIAP1
N-Boc-SBP-0636457-OH      
cIAP1
(S,R,S)-AHPC dihydrochloride
VHL
     
cIAP1 ligand 2      
cIAP1
Pomalidomide-6-OH    
Cereblon
  98.09%
Pomalidomide-6-O-CH3    
Cereblon