Ligands for E3 Ligase Inhibitors

von Hippel-Lindau (VHL)

MDM2

Cereblon

IAP

KLHDC2

Fbxo3

RNF4

DCAF11

DCAF1

UHRF1

Ligands for E3 Ligase Degraders, Controls, Inhibitors, Modulators & Chemicals

Product Name	von Hippel-Lindau (VHL)	MDM2	Cereblon	IAP	KLHDC2	Fbxo3	RNF4	DCAF11	DCAF1	UHRF1	Purity
Lenalidomide			Cereblon								99.95%
Pomalidomide			Cereblon								99.96%
CC-885			Cereblon Cereblon								99.85%
Eragidomide			Cereblon								99.86%
E3 ligase Ligand 32	VHL										99.95%
BMS-986397			Cereblon Cereblon
N-Me-Thalidomide 4-fluoride			Cereblon Cereblon
Iberdomide			Cereblon Cereblon								99.54%
VH-298	VHL										99.78%
PT-179			Cereblon Cereblon								99.91%
VH032	VHL										99.64%
(S,R,S)-AHPC-Me hydrochloride	VHL										99.59%
(S,R,S)-AHPC monohydrochloride	VHL										99.83%
Golcadomide			Cereblon
(S,R,S)-AHPC	VHL										99.13%
ALV2			Cereblon Cereblon								98.07%
Lenalidomide hemihydrate			Cereblon								99.67%
(S,R,S)-AHPC-Me	VHL										99.48%
ALV1			Cereblon
Lenalidomide-Br			Cereblon								99.86%
VH032-cyclopropane-F	VHL										99.92%
ZXH-1-161			Cereblon Cereblon								98.43%
BC-1215						Fbxo3					99.93%
(S,S,S)-AHPC hydrochloride	VHL										99.42%
Lenalidomide-OH			Cereblon								99.48%
(S)-Thalidomide			Cereblon								99.65%
(S,R,S)-AHPC-propargyl	VHL										99.48%
NV03										UHRF1	98.82%
Biotin-Thalidomide			Cereblon								99.65%
cIAP1 ligand 1				cIAP1							99.90%
Nutlin carboxylic acid		MDM2									98.63%
VH 101, acid	VHL										98.37%
DCAF1 binder 1			Cereblon Cereblon								99.12%
VHL Ligand 8	VHL										98.04%
VHL-IN-1	VHL										99.78%
Lenalidomide-I			Cereblon Cereblon								99.90%
VL285	VHL										98.84%
KB02-COOH			Cereblon								99.39%
CCW16							RNF4				98.63%
PD 4'-oxyacetic acid			Cereblon Cereblon								99.69%
(S,R,S)-AHPC-Boc	VHL
(S,R,S)-AHPC-Me dihydrochloride	VHL										99.84%
CC-3060			Cereblon Cereblon								99.7%
TD-106			Cereblon Cereblon								98.67%
AR antagonist 1 hydrochloride	VHL										99.53%
CC-17369			Cereblon								98.13%
VHL Ligand 14	VHL										99.93%
Lenalidomide-F			Cereblon
VH 101, thiol	VHL										98.66%
Cereblon inhibitor 1			Cereblon								99.19%
(R,S,S)-VH032	VHL
Pomalidomide-5-OH			Cereblon								99.46%
Pomalidomide-d₃			Cereblon Cereblon								≥99.0%
E3 ligase Ligand 23			Cereblon								99.71%
VL285 Phenol	VHL										98.56%
CRBN modulator-1			Cereblon								98.00%
2-Methoxyphenyl dihydrouracil			Cereblon
E3 ligase Ligand 18			Cereblon								99.22%
Thalidomide-pyrrolidine hydrochloride			Cereblon Cereblon								≥98.0%
Lenalidomide 5'-piperazine			Cereblon Cereblon								99.92%
Thalidomide-d₄			Cereblon								98.00%
Lenalidomide-d₅			Cereblon Cereblon								99.32%
E3 ligase Ligand 8				IAP IAP							99.32%
Cereblon inhibitor 2			Cereblon Cereblon								98.86%
CRBN ligand-9			Cereblon Cereblon								≥98.0%
Thalidomide-piperazine hydrochloride			Cereblon								98.27%
VH032 thiol	VHL
Pomalidomide-6-OH			Cereblon								98.09%
Thalidomide (Standard)			Cereblon Cereblon
(R)-Thalidomide			Cereblon								99.80%
Lenalidomide (Standard)			Cereblon Cereblon
Lenalidomide hydrochloride			Cereblon
Pomalidomide-d₄			Cereblon Cereblon
(S,R,S)-AHPC TFA	VHL
Aster-A Ligand-3			Cereblon
E3 ligase Ligand 26			Cereblon
E3 ligase Ligand 42			Cereblon
E3 ligase Ligand 22			Cereblon
Pomalidomide-5-O-CH3			Cereblon
E3 ligase Ligand 10				IAP IAP
DA-PROTAC	VHL
(4R,5S)-Nutlin carboxylic acid		MDM2
PROTAC CRBN ligand-2			Cereblon
Thalidomide-(2)piperidine			Cereblon Cereblon
HOXB7 8–25		MDM2
E3 ligase Ligand 14				IAP IAP
Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride			Cereblon Cereblon
E3 ligase Ligand 38			Cereblon
Lenalidomide-¹³C₅,¹⁵N			Cereblon Cereblon
(S,R,R)-VH032	VHL
E3 ligase Ligand 37	VHL
E3 ligase Ligand 36	VHL
E3 ligase Ligand PG			Cereblon, IC₅₀: 2.191 μM
(S,R,S)-AHPC-Ala	VHL
Pomalidomide-piperazine			Cereblon Cereblon
Bestatin-amido-Me				cIAP1
E3 ligase Ligand 31			Cereblon
Cyclopropane-(S,R,S)-AHPC	VHL
E3 ligase Ligand 44	VHL
cis VH-298	VHL
E3 ligase Ligand 27	VHL
VH032 analogue-2	VHL
E3 ligase Ligand 25			Cereblon
(S)-Deoxy-thalidomide-Br			Cereblon
Acepromazine-OTs			Cereblon
E3 ligase Ligand 21			Cereblon
VH032-CH2-Boc	VHL
(S)-Deoxy-thalidomide			Cereblon Cereblon
MV-1-NH-Me				cIAP1
E3 ligase Ligand 13				IAP IAP
(R)-Pomalidomide-pyrrolidine			Cereblon Cereblon
(S,R,S,R)-AHPC-Me	VHL
CRBN ligand-11			Cereblon
Thalidomide-azetidine-CHO			Cereblon Cereblon
MY-11B									DCAF1
Ru-Poma			Cereblon Cereblon
E3 ligase Ligand 45	VHL
VH032 analogue-1	VHL
BCL-xL/BCL-2 ligand 1	VHL
HL389			Cereblon
(3S)Lenalidomide-5-Br			Cereblon
VH032-NH-CO-CH2-NHBoc	VHL
GNE7599	VHL
tDHU, acid			Cereblon Cereblon
Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride			Cereblon Cereblon
E3 ligase Ligand 34	VHL
Me-SJ46411	VHL
OICR-8268-acrylic acid	VHL
RR-11055			Cereblon Cereblon
N-Boc-SBP-0636457-OH				cIAP1
E3 ubiquitin ligase binder-1			Cereblon Cereblon
Thalidomide-methylpyrrolidine			Cereblon Cereblon
SJF-0661	VHL
(S,R,S)-AHPC-Ac	VHL
Pomalidomide-d₅			Cereblon Cereblon
E3 ligase Ligand 33	VHL
(S,R,S)-AHPC-O-CF3	VHL
(S,R,S)-AHPC dihydrochloride	VHL
E3 ligase Ligand 35	VHL
SJ46411-Br	VHL
E3 ligase Ligand 43	VHL
E3 ligase Ligand 7								DCAF11
E3 ligase Ligand 41			Cereblon
AS1411-C4-VH032		MDM2
VHL-SF2	VHL
OICR-8268			Cereblon Cereblon
cIAP1 ligand 2				cIAP1
L321			Cereblon
CRBN ligand-1			Cereblon Cereblon
Pomalidomide-¹⁵N,¹³C₅			Cereblon Cereblon
cIAP1 ligand 4				IAP IAP
Pomalidomide-6-O-CH3			Cereblon
E3 ligase Ligand 29	VHL
SOS1 Ligand intermediate-2	VHL
Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride			Cereblon Cereblon
AR antagonist 1	VHL
BWA-522 intermediate-1			Cereblon Cereblon								99.27%
Pomalidomide (Standard)			Cereblon Cereblon
Phenyl-glutarimide 4'-oxyacetic acid			Cereblon Cereblon
SJ6145					KLHDC2
E3 ligase Ligand 30	VHL
Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph	VHL
(S,R,S)-AHPC(Me)-amido-C2-acid	VHL
SOS1 Ligand intermediate-1	VHL
Thalidomide-5-piperazine			Cereblon Cereblon

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